Medical Macrosimulation is a relatively new method of training healthcare professionals that, through a high degree of realism and interactivity, enables the acquisition of technical knowledge, improvement of human factors management, and maximization of learning outcomes.

This innovative teaching methodology reproduces a virtually infinite series of clinical situations (called "scenarios") through the use of high-tech mannequins that reproduce the patient in life-size. The mannequins simulate breathing, peripheral pulses, and heart sounds; they are able to answer questions thanks to an "actor" in the control room who impersonates the patient and react appropriately to the learner's actions.

The mannequins can be used to monitor vital signs, measure blood pressure, perform electrical cardioversion, external pacing, defibrillation, cardiopulmonary resuscitation, and more.

Participants address the pathological conditions covered in the course from a diagnostic and therapeutic perspective, and coordinate the various professionals present on the scene. The clinical conditions of the mannequin, regulated by the instructors, vary in real time depending on the actions of the students.